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Identification, charecterisation and antibiotic suceptibility of shigella species isolated from stool samples in children

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dc.contributor.author Deepa, Patil P.
dc.contributor.author Lava R.
dc.date.accessioned 2015-07-27T17:52:40Z
dc.date.available 2015-07-27T17:52:40Z
dc.date.issued 2012
dc.identifier.citation International Journal of Biological and Medical Research. 2013; 3(2): 1640-1643. en_US
dc.identifier.issn 0976-6685
dc.identifier.uri http://hdl.handle.net/123456789/648
dc.description.abstract Background and Objectives: Shigellosis, an acute diarrhoeal disease, remains a major public health problem in developing countries. The increasing levels of antimicrobial resistance of Shigella isolates have complicated the treatment of shigellosis. The purpose of present study was to determine the incidence of Shigella species and their antimicrobial resistance patterns for the better management of shigellosis in children. Material and methods: The study was conducted in a tertiary care hospital in the Department of Microbiology, between June 2009 to May 2010. Stool samples were collected from paediatric age group. Shigella isolation, identification and speciation were done by using simplified phenotypic identification scheme and antibiotic sensitivity pattern of these isolates was studied. Results : A total of 128 stool samples were studied, out of which Shigella species accounted for 10.1%, E.coli accounted for 57.8%, Klebseilla species accounted for 20.3% and Pseodomonas species accounted for 15%.Resistance pattern of Shigella species to various drugs were, Co –trimoxazole (76.9%), Doxycycline (69.2%), Amoxycillin (100%), Cefotaxime (69.2%), Ceftriaxone (69.2%), Gentamicin (61.5%), Nalidixic acid (100%) and Ciprofloxacin (69.2%). All the Shigella isolates were sensitive to Amikacin. Conclusion : The predominant shigella species isolated in this study was Shigella flexneri. The present study demonstrates that Shigella species showing significant increase in resistance to several commonly used antimicrobial agents. The results suggest reconsideration of the empiric use of these antimicrobial drugs for the treatment of Shigellosis and the findings, stress the need for ongoing drug resistance surveillance. en_US
dc.language.iso en en_US
dc.publisher BioMed Scidirect Publications en_US
dc.subject Shigellosis en_US
dc.subject Shigella flexneri en_US
dc.subject Shigella boydii en_US
dc.subject Shigella dysenteriae en_US
dc.subject Bacillary dysentery
dc.title Identification, charecterisation and antibiotic suceptibility of shigella species isolated from stool samples in children en_US
dc.type Article en_US


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