Study of lipid profile in psoriasis patients

Abstract

Psoriasis is a skin disease with the population prevalence. Its prevalence in the population is affected by genetic, environmental, viral, infectious, immunological, biochemical endocrinological and psychological factors as well as alcohol and drug abuse.In the recent years, psoriasis has been recognised as a systematic disease associated with numerous multiorgan abnormality and complications. With growing awareness of psoriasis and its impact on life span especially in India, special attention is being paid to early detection, management and treatment of Psoriasis. The aim of this study was to measure the serum total cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL) and low density lipoprotein (LDL). 70 clinically diagnosed psoriatic patients and 70 healthy individuals were recruited as control. Out of total 70 Psoriasis patients included in study, 24 were mild, 23 moderate and remaining 23 were severe psoriatic patients. The results were compared between psoriasis patients and healthy controls by using ‘Z’ test. Serum total cholesterol, triglyceride, low density lipoprotein were significantly increased in psoriasis patients as compared to control group. But serum High density lipoprotein were significantly decrease in Psoriasis patients compared with controls. The study found abnormal lipid profile which is risk factor for cardiovascular diseases (CVD) in psoriasis patients