Abstract:
The present study was undertaken to study the free radical activity in malaria patients
suffering from plasmodium falciparum (n=14) and plasmodium vivax (n=21) against the healthy
control subjects (n=25). Lipid peroxidation was assessed by measuring serum lipid peroxide in
both groups of malaria patients by using Malondialdehyde as standard. The serum
Ceruloplasmin is also studied along with serum Lipid peroxidation. The level of serum Lipid
peroxidation was significantly high (p<0.001) in patients with Plasmodium falciparum malaria as
compared to Plasmodium vivax infected patients and healthy controls. Increase in serum Lipid
peroxidation may be due to over activity of free radical, which corresponds with severity of tissue
damage while increase in serum Ceruloplasmin could be due to acute phase response in
malaria.
