Abstract:
Advanced oxidation protein product (AOPP) and protein carbonyl (PC) as protein oxidation
products (PPP) and antioxidants such as reduced glutathione (GSH),total thiol (TT) and
albumin levels were analyzed in 27 patients with diagnosed primary brain tumor and 25
normal healthy age and sex matched controls. Statistically significant increased (p-0.001)
levels of AOPP and PC were noted; GSH and TT levels were increased (p-0.833) & (p-0.032)
respectively with decreased albumin levels (p-0.629).Hence increased oxidative stress
signified by increased PPP and altered antioxidant levels may have a role in etipathogenesis
of primary brain tumor.
