Transfusion induced Graft versus host disease – case report in a 2 year child

dc.contributor.author	Kikkeri, Naveen Narayanashetty
dc.contributor.author	Kabbin, Gautam Mohan
dc.contributor.author	Kulkarni, Vijay
dc.contributor.author	Pai, Varadraj V.
dc.contributor.author	Rao, Ravikala V.
dc.date.accessioned	2012-12-29T09:28:24Z
dc.date.available	2012-12-29T09:28:24Z
dc.date.issued	2012
dc.identifier.citation	Transfusion and Apheresis Science. 2012; 47: 17–19.	en_US
dc.identifier.issn	1473-0502
dc.identifier.uri	http://hdl.handle.net/123456789/307
dc.description.abstract	Graft-versus-host disease (GVHD) is a rare, almost always fatal complication of a blood transfusion. It occurs much more commonly after bone marrow transplantation, a setting in which it is less severe—mortality rate of 20–25% following transplantation versus 80– 90% when associated with a transfusion. Transfusion associated GVHD occurs in two set- tings: when the recipient is immunodeficient; and when there is a specific type of partial HLA matching between the donor and recipient. Here we present a case of transfusion associated GVHD which developed when a 2 year old immunocompetent girl was given whole blood which was taken by his father. Inspite of very intense therapy with parental steroids and oral cyclosporine the child succumbed to death.	en_US
dc.language.iso	en	en_US
dc.publisher	Elsevier	en_US
dc.subject	Blood transfusion-adverse effects	en_US
dc.subject	Graft-versus-host disease	en_US
dc.title	Transfusion induced Graft versus host disease – case report in a 2 year child	en_US
dc.type	Article	en_US