Abstract:
Objective: Gestational diabetes mellitus is defined as “carbohydrate
intolerance resulting in hyperglycemia of variable severity with onset or first
recognition during pregnancy, whether or not insulin is used and regardless
of whether diabetes persists after pregnancy. There is evidence that
asymptomatic hyperglycemia during pregnancy leads to important morbidity
in the mother and foetus. Hence, early detection and treatment of GDM will
definitely reduce the complications and bring down the morbidity.
Methods: Test was performed using 100 gm oral glucose. Blood samples
were taken at 1hr, 2hr and 3hr as per standard protocol. Blood glucose was
measured by glucose oxidase enzymatic method and all the values were
tabulated and plotted on a graph. Interpretation was done using Carpenter
and Coustan Criteria.
Results: Out of the 96 women, 15 women were diagnosed as GDM. 5 out of
them showed atypical pattern in OGTT curve. Similar such patterns were also
seen in 5 normal subjects.
Conclusion: In GDM with mild to moderate elevation in fasting plasma
glucose, fasting plasma insulin is elevated in parallel. The presence of IGT in
pregnancy is predictive of poor pregnancy outcomes. High 2 nd hour glucose
could be a marker of poor health.
